(625) Positive Correlative Volume-Outcome Relationship for Multiorgan Heart Transplantation

PurposeTransplant center volume is associated with improved survival after isolated heart transplant, but its impact on multiorgan transplant outcomes unknown. This study examines the of institutional outcomes.MethodsAdult patients undergoing first time from 2011-2021 were identified in United Network for Organ Sharing database. For each year, centers classified as low-, medium-, or high-volume if they performed <3, 3-5, ≥6 transplants that respectively. Volume cutoffs defined by tertiles 2021. Graft failure was death re-transplantation.ResultsDuring period, 1817 at 104 centers, including 477 (26%) 597 (33%) and 743 (41%) centers. The proportion increased 10% 2011 to 62% Recipient sex, race, body mass index did not vary (all p>0.05). Patients more likely be intensive care unit pre-transplant (59% vs. 44%, p<0.001) have shorter waitlist times (46 94 days, than those low-volume higher combined medium- compared both 30 days (96% 93%, p=0.004) 1 year (88% 84%, p=0.020) post-transplant. Compared low volume, medium high protective against 30-day graft univariate (hazard ratio 0.72 [0.55-0.95]) multivariate 0.53 [0.33-0.84]) Cox regression. Total predictive (p>0.05).ConclusionHigher total early transplant. Transplant outcomes. Adult re-transplantation. During (p>0.05). Higher